Human Tonsil v2 Reference Explorer

Annotation Markers

celltype.l1
LabelMarkers
aDCLAMP3, CCR7, FSCN1, SLCO5A1, DUSP5, PRDM16, CCL19, TREML1, SYNPO2, CCL22
B activatedFCER2, IGHD, CD83, NFKB2, CD72, CD69, MYC, EGR3, REL, HLA-DQB1
B memoryCD27, BANK1, MARCH1, CD24, TCF4, TNFRSF13B, BLK, CCR6, TLR10, TBC1D9
B naiveIGHD, IGHM, BANK1, FCER2, TCL1A, CD79B, MEF2C, MS4A1, CD79A, CD22
CD4 naiveCD3D, CD3E, CD3G, CD2, IL7R, TCF7, CCR7, LEF1, NOSIP, GIMAP7
CD4 Non-TFHCD3D, CD3E, CD3G, MAF, IL7R, RORA, IL17A, CCR4, GATA3, PRDM1
CD4 TCMCD3D, CD3G, TCF7, IL7R, ANK3, S100A4, PASK, IL6ST, FYB1, ANXA1
CD4 TFHCD3D, CD3E, CD2, TIGIT, IL6ST, PDCD1, TOX2, ICOS, CXCR5, CXCL13
CD4 TFH MemCD3D, CD3E, KLRB1, IL32, MAF, TOX2, ICOS, TNFRSF1B, IKZF3, CEP128
CD4 TREGCD3D, CD3E, CD2, CYTOR, IL10, FOXP3, CTLA4, IL2RA, RGS1, TNFRSF4
CD8 naiveCD8B, CD8A, CD3D, CD3E, IL7R, CCR7, LEF1, TCF7, SELL, NOSIP
CD8 TCD8A, CD8B, CD3G, CD3E, CCL5, GZMK, NKG7, KLRG1, PRF1, KLRK1
CD8 TCMCD8A, CD8B, CD3D, CD3E, IL7R, ANXA1, S100A4, FYB1, S100A6, GIMAP7
Cycling DZ GCBAICDA, MME, RGS13, MEF2B, STMN1, MKI67, PCLAF, NUSAP1, TOP2A, HMGB2
Cycling FDCFDCSP, CLU, CXCL13, CSTA, IGFBP7, TOP2A, MKI67, PCLAF, PCNA, HMGB1
Cycling myeloidLYZ, CST3, LGALS2, MS4A6A, TYROBP, S100B, TOP2A, MKI67, PCLAF, PCNA
Cycling TCD3D, CD3E, CD3G, CD2, TOP2A, MKI67, PCLAF, LCK, CD28, HMGB2
DCLYZ, CST3, LGALS2, CPVL, FGL2, AIF1, LST1, SAMHD1, GSN, FCER1G
dnTCD3G, CD3D, CD3E, HAVCR2, GPR183, CD28, TCF7, BCL11B, GZMK, NUCB2
DZ GCBSUGCT, MEF2B, NEIL1, SEC14L1, AICDA, BCL7A, MME, BACH2, TCL1A, CD38
DZtoLZ GCB transitionMEF2B, RGS13, SERPINA9, LMO2, HMCES, KLHL6, LRMP, FGD6, MARCKSL1, NEIL1
EpithelialSPINK5, KRT19, SPRR3, KRT13, KRT18, SPRR1B, S100A9, CSTA, S100A8, LCE3D
FCRL4/5+ B memoryFCRL4, FCRL5, ITGAX, ITGB2, TNFRSF13B, BHLHE41, IFI30, ACP5, PTPN1, BANK1
FDCCLU, FDCSP, PTGDS, CXCL13, CR2, MARCKS, MAP1LC3A, IGFBP7, COL27A1, VCAM1
GranulocytesSOD2, NAMPT, CXCL8, S100A9, G0S2, S100A8, TYROBP, SLPI, MXD1, CXCR2
ILCIL7R, FCER1G, TRDC, TNFRSF18, GNLY, AHR, CD200R1, ANXA1, RORC, IL23R
LZ GCBLMO2, RGS13, MEF2B, BCL2A1, SERPINA9, GMDS, FGD6, RFTN1, PLEK, LRMP
LZtoDZ GCB transitionBATF3, MYCBP, NME1, FABP5, PCLAF, MCM7, EBI3, PAICS, PCNA, LMO2
MAIT/TRDV2+ gdTKLRB1, TRDC, TRGC2, TRGC1, IL18RAP, CEBPD, ZBTB16, RORA, CXCR6, NKG7
MastCPA3, TPSB2, TPSAB1, MS4A2, FCER1G, TYROBP, HPGD, KIT, HPGDS, RAB32
Mono/MacroLYZ, CST3, TYROBP, AIF1, FCER1G, CD68, IL18, TMEM176B, LGALS1, VCAN
NKKLRF1, KLRD1, KLRK1, NKG7, GNLY, FCGR3A, PRF1, CCL5, CX3CR1, GZMA
NK_CD56brightGNLY, KLRF1, KLRD1, NKG7, NCAM1, TYROBP, CTSW, XCL1, EOMES, AREG
non-TRDV2+ gdTTRDC, TRGC1, TRGC2, CCL5, KLRK1, CD7, NKG7, KLRD1, CTSW, CST7
PBXBP1, MZB1, FKBP11, SDF2L1, TXNDC5, DERL3, CENPA, PCLAF, JCHAIN, MANF
PCDERL3, FKBP11, XBP1, MZB1, PRDX4, TXNDC5, SEC11C, IRF4, SSR3, PRDM1
PC/doubletMZB1, DERL3, XBP1, FKBP11, PRDX4, TXNDC5, LINC02362, SDC1, SSR4, IGHGP
PDCLILRA4, IL3RA, IRF8, CST3, FCER1G, SERPINF1, ITM2C, IRF7, SMPD3, PLD4
preB/TIGLL1, ACSM3, MYB, VPREB1, ARPP21, RAG1, AKAP12, DNTT, BMP3, CD1B
preGCBPRDX1, YBX1, NME2, HSP90AB1, MIF, NPM1, EIF4A1, FABP5, LMO2, BASP1
preMBC/doubletMEF2B, RGS13, BASP1, LRMP, TCL1A, MARCKSL1, SWAP70, CD22, TNFRSF13C, RFTN1
prePBRGS13, MEF2B, RASSF6, HMCES, CCDC88A, XBP1, VDR, PRDM1, FAM3C, CCDC144A
celltype.l2
LabelMarkers
aDC1LAMP3, RASSF4, FSCN1, MARCKS, TNFAIP2, TYROBP, CSF2RA, GSN, TMEM176B, IDO1
aDC2S100B, LAMP3, CCL22, SHTN1, S100A2, SDC4, PRDM16, GJA1, FLT3, AC090559.1
aDC3FSCN1, LGALS2, IDO1, RASSF4, CST3, CCL19, TYROBP, LAMP3, TMEM176A, TMEM176B
Basal cellsS100A8, KRT5, SFN, S100A2, KRT14, SPINK5, S100A14, KRT6A, S100A16, KRT13
C1Q Slan-likeLYZ, CST3, C1QA, C1QC, C1QB, TYROBP, AIF1, FCER1G, MMP9, TMEM176B
CD14+CD55+ FDCVCAM1, IGFBP7, RARRES2, SERPINE2, CXCL13, ANKRD29, CXCL14, NOVA1, TNFAIP2, CALD1
CD16-CD56+ NKGNLY, KLRD1, NKG7, TYROBP, CTSW, TRDC, FCER1G, ID2, XCL2, PRF1
CD16-CD56dim NKKLRD1, TYROBP, NKG7, GNLY, TRDC, CTSW, FCER1G, KLRK1, IL2RB, KLRB1
CD16+CD56- NKNKG7, KLRD1, GNLY, GZMA, PRF1, CST7, GZMB, CTSW, CCL4, GZMH
CD8 TfGZMK, CST7, CCL5, NKG7, GZMA, IL32, CCL4, EOMES, SH2D1A, CD8A
CM CD8 TIL7R, CCL5, IL32, ANXA1, GIMAP7, CD3D, GIMAP4, CD3E, CD3G, CD2
CM Pre-non-TfhIL7R, GIMAP7, CD3D, IL32, CD3G, GIMAP4, CD3E, FYB1, CD2, ANXA1
CM PreTfhIL7R, FYB1, GIMAP7, CD3D, CD3G, BCL11B, CD3E, IL6ST, IL32, GIMAP4
COL27A1+ FDCTNFAIP2, CLU, MAP1LC3A, ANKRD29, NFIA, FDCSP, DST, NOVA1, TPM1, EPHX2
CryptCSTA, KRT19, CCL20, IDO1, MT3, IFI27, FXYD3, SPINK5, S100P, HPGD
csMBCBANK1, TNFRSF13B, ADAM28, LINC01781, AIM2, MARCH1, SCIMP, BHLHE41, ARHGAP24, SMIM14
csMBC FCRL4/5+FCRL4, TNFRSF13B, BHLHE41, FCRL5, ENTPD1, CCR6, CCDC50, PTPN1, ZEB2, CAPG
CyclingLYZ, CST3, LGALS2, MS4A6A, TYROBP, S100B, FCER1G, C1QA, C1QC, IGSF6
cycling FDCCLU, FDCSP, PTGDS, CSTA, IGFBP7, RARRES2, CXCL13, SERPINE2, G0S2, MAP1LC3A
cycling TCD3D, CD3E, CD3G, CD2, FYB1, IL32, STMN1, LAT, BCL11B, TRAC
DC recruiters CD8 TNKG7, CCL5, GZMK, CST7, GZMA, KLRK1, CCL4, IL32, KLRG1, KLRD1
DC1 matureCPVL, FGL2, DNASE1L3, LGALS2, CST3, SHTN1, LYZ, IDO1, C1orf54, ID2
DC1 precursorLGALS2, CST3, LYZ, DNASE1L3, CPVL, IDO1, S100B, RAB32, RGCC, C1orf54
DC2TYROBP, LGALS2, CST3, LYZ, FGL2, FCER1G, IGSF6, CPVL, JAML, MNDA
DC3FCER1G, CPVL, CFP, TYROBP, IGSF6, FCN1, LGALS2, AC020656.1, VCAN, IL1B
DC4TYROBP, FGL2, LYZ, SERPINA1, LGALS2, CST3, IGSF6, FCER1G, CPVL, KCTD12
DC5LST1, JAML, LYZ, CST3, TYROBP, GSN, HCK, PAK1, CLEC4A, FGL2
DNGZMK, NUCB2, MT2A, CD3G, LYST, GIMAP5, SH2D1A, GIMAP4, CD3D, GIMAP7
DZ cell cycle exitSTMN1, PTTG1, HMGB2, H2AFV, RGS13, SEC14L1, CENPF, BIRC5, AICDA, MEF2B
DZ early G2MphaseTOP2A, UBE2C, TPX2, MKI67, CDK1, NUSAP1, ASPM, HIST1H1B, CENPF, GTSE1
DZ early SphaseMCM4, PCLAF, GINS2, STMN1, HELLS, MCM7, SLBP, CDCA7, CLSPN, MCM3
DZ late G2MphaseCDC20, CCNB2, CCNB1, HMMR, TPX2, CENPF, CDKN3, TOP2A, ASPM, BIRC5
DZ late SphaseRRM2, HIST1H1B, MKI67, PCLAF, TYMS, NUSAP1, TK1, CLSPN, MCM7, CENPM
DZ migratory PC precursorEPDR1, IGHVIII-38-1, AC246787.2, LINC02362, DERL3, FKBP11, SLAMF7, IGLV1-50, FNDC3B, IGHGP
DZ non proliferativeSUGCT, MEF2B, NEIL1, SEC14L1, AICDA, BCL7A, MME, BACH2, TCL1A, CD38
DZ_LZ transitionMEF2B, RGS13, SERPINA9, LMO2, HMCES, KLHL6, LRMP, FGD6, MARCKSL1, NEIL1
Early GC-commited NBCEGR3, CD83, PHACTR1, CD69, IGHD, FCER2, CD72, NFKBID, BANK1, DUSP2
Early MBCHTR3A, NEIL1, BANK1, IGHD, HRK, ACP5, SMIM14, CR2, LTB, MIR3681HG
Early PC precursorRASSF6, NKX6-3, FMNL2, FRZB, SPARCL1, TMEM52B, PPP1R17, LINC01484, ETV7, PRDM1
Eff-TregsMAF, CD2, IL32, CD3D, CD3E, CYTOR, TNFRSF1B, CD3G, FYB1, PBXIP1
Eff-Tregs-IL32IL32, CD3D, S100A4, RTKN2, CD3E, CD2, PRDM1, CD3G, TIGIT, FYB1
EM CD8 TNKG7, CCL5, GZMA, CST7, GZMH, CTSW, CCL4, GNLY, PRF1, KLRD1
FDCCLU, FDCSP, CSTA, PTGDS, CXCL13, IGFBP7, RARRES2, SERPINE2, MARCKS, G0S2
FDCSP epitheliumS100A8, KRT6A, S100A14, SFN, SPINK5, S100A16, PERP, SPRR1B, SPRR2A, RHCG
FRCC5AR2, SPINK5, PBX1, LTF, NFASC, FRK, MIR205HG, ST5, ACOT11, ARHGAP29
GC DZ NoproliIGHV1-45, AL157373.2, AC125437.3, MEX3A, RFX3-AS1, TCL6, AP000424.1, C1orf61, DCAF12, NEIL1
GC-commited NBCCD83, FCER2, NME1, PHACTR1, SYNGR2, CCND2, DDX21, CD72, PARP14, MIR155HG
GC-Tfh-OX40CD3D, CD2, GBP2, TIGIT, ITM2A, MAF, CD200, SRGN, CD3E, TBC1D4
GC-Tfh-SAPTOX2, CD3D, CD2, TIGIT, PDCD1, ITM2A, MAF, CD3E, LAT, CD3G
IFN+ CD8 TIFIT1, CCL5, GZMK, IFI6, IFI44L, NKG7, RSAD2, IFI44, CST7, GZMA
IFN1+ PDCGZMB, LILRA4, TYROBP, DNASE1L3, FCER1G, CST3, SERPINF1, SMPD3, IL3RA, LILRB4
IgD PC precursorDERL3, FKBP11, SDF2L1, MANF, DNAJB9, PRDX4, TXNDC5, CRELD2, AC012236.1, SLAMF7
IgG+ PC precursorDERL3, FKBP11, XBP1, TXNDC5, MZB1, PDIA4, AC012236.1, JCHAIN, SELENOS, RRBP1
IgM+ early PC precursorVPREB1, ALDOB, C4BPB, LINC01551, RASSF6, NKX6-3, GIPC2, LINC02362, ABCA12, SPARCL1
IgM+ PC precursorRASSF6, LINC02362, CKAP4, VDR, CCR10, LINC01484, ADM, RHBDL1, CTHRC1, AP000542.2
IL7R DCTYROBP, CST3, C15orf48, LYZ, LGALS2, CSF2RA, FCER1G, CPVL, FPR1, IL4I1
ILC1KLRB1, FCER1G, TYROBP, CTSW, TRDC, ID2, TNFRSF18, GNLY, XCL2, FXYD7
ITGAX Slan-likeRASSF4, DST, IL18, ITGAX, TFEC, DMXL2, TLR4, LINC00996, NR1H3, NAIP
LZRGS13, LMO2, MEF2B, SERPINA9, GMDS, FGD6, KLHL6, BCL2A1, LRMP, RFTN1
LZ proliferativeNME1, FABP5, STMN1, HNRNPAB, MCM7, PAICS, HELLS, RANBP1, MKI67, MCM3
LZ_DZ reentry commitmentLMO2, BCL2A1, RGS13, NME1, GMDS, MEF2B, DUSP2, CD83, OTULIN, FABP5
LZ_DZ transitionPCLAF, NME1, FABP5, PCNA, MCM7, MCM4, TYMS, PAICS, STMN1, GMNN
M1 MacrophagesTYROBP, FCER1G, SERPINA1, LYZ, S100A9, TIMP1, C15orf48, S100A8, IER3, LGALS3
MAIT/CD161+TRDV2+ gd T-cellsCCL5, NKG7, GZMK, GZMA, KLRB1, IL7R, IL32, S100A4, CST7, ANXA1
MastCPA3, TPSB2, TPSAB1, MS4A2, FCER1G, CLU, VWA5A, LTC4S, TYROBP, HPGD
Mature IgA+ PCDERL3, FKBP11, MZB1, XBP1, JCHAIN, PRDX4, TXNDC5, SEC11C, IGHA1, MANF
Mature IgG+ PCFKBP11, PRDX4, DERL3, XBP1, MZB1, IGHG4, IGHG3, ITM2C, SEC11C, IGHG1
Mature IgM+ PCDERL3, FKBP11, LINC02362, AC147651.1, AC074212.1, TXNDC5, XBP1, PRDX4, SLAMF7, DNAJB9
MBC derived early PC precursorDERL3, MZB1, FKBP11, XBP1, PRDX4, IGHG3, SSR4, IGHGP, IGHG1, IGHG4
MBC derived IgA+ PCDERL3, TXNDC5, FKBP11, XBP1, MZB1, SELENOS, PRDM1, JCHAIN, PDIA4, PRDX4
MBC derived IgG+ PCFKBP11, DERL3, XBP1, PRDX4, MZB1, TENT5C, ITM2C, TXNDC5, SELENOS, SEC11C
MBC derived PC precursorDERL3, FKBP11, TXNDC5, LINC02362, SLAMF7, FNDC3B, SDC1, XBP1, TENT5C, MZB1
MBC FCRL5+FCRL5, SCIMP, HOPX, CPNE5, IFI30, BANK1, BHLHE41, CTSH, TNFRSF13B, HLA-DQB1
MMP Slan-likeTMEM176B, C1QA, LYZ, TYROBP, CST3, C1QB, FCER1G, CD68, C1QC, MMP9
MonocytesTYROBP, LYZ, FCER1G, S100A9, CST3, FGL2, FCN1, MNDA, S100A8, AIF1
MRCCALD1, DST, IGFBP7, COL1A2, COL6A3, DCN, ROBO1, RARRES2, ABI3BP, AEBP1
NaiveGIMAP7, CD3D, CD3E, CD3G, FYB1, IL7R, GIMAP4, TCF7, BCL11B, CD7
Naive CD8 TCD8B, CD3D, CD3E, GIMAP7, CD3G, CD8A, IL7R, CD7, LINC02446, KLRK1
NBCIGHD, IGHM, TCL1A, BANK1, FCER2, HLA-DQB1, LINC02397, CD72, HLA-DQA1, HVCN1
NBC CD229+LINC01857, PARP15, OAS1, FCRL5, FCMR, LILRA4, ACP5, FCRL2, PHACTR1, TCF4
NBC early activationIGHD, IGHM, ADAM28, BANK1, TCL1A, FCER2, LINC00926, HVCN1, LINC02397, MARCH1
NBC IFN-activatedIFIT3, IFI44L, IFIT1, ISG15, XAF1, MX1, SAMD9L, EPSTI1, STAT1, MX2
ncsMBCTNFRSF13B, ARHGAP24, BANK1, CD24, TCF4, FCRL2, CD1C, IGHM, RALGPS2, CCDC50
ncsMBC FCRL4/5+TNFRSF13B, FCRL4, ACP5, CCR6, CCDC50, BHLHE41, PTPN1, BANK1, IFI30, FCRL5
NeutrophilsSOD2, NAMPT, CXCL8, S100A9, G0S2, S100A8, TYROBP, FCER1G, MXD1, GLUL
NKp44- ILC3AC244502.1, LINC00299, IGFBP7, KIT, IL23R, DPPA4, RORC, HOXA9, AC004540.2, MRC2
NKp44+ ILC3TYROBP, KLRB1, CTSW, IL7R, ID2, TNFRSF18, FCER1G, LINC00299, PCDH9, JAML
Outer surfaceIL1RN, SPRR1B, SPRR3, SPRR2D, SPRR2E, SPRR2A, NCCRP1, LCE3D, LCN2, RHCG
PBXBP1, MZB1, FKBP11, SDF2L1, DERL3, TXNDC5, SEC11C, JCHAIN, MANF, SSR3
PB committed early PC precursorVDR, CCR10, CFAP54, SPARCL1, KRT5, DENND6B, RASSF6, PRDM1, CKAP4, CD9
PC committed Light Zone GCBCRGS13, MEF2B, RASSF6, HMCES, CCDC88A, DHRS9, KLHL6, LRMP, AC023590.1, FAM3C
PDCGZMB, LILRA4, IL3RA, TYROBP, CST3, FCER1G, SERPINF1, ITM2C, MPEG1, IRF7
preBIGLL1, ACSM3, VPREB1, ARPP21, AKAP12, BMP3, RAG1, DNTT, RIMS3, RARA-AS1
Precursor MBCsMEF2B, RGS13, BASP1, LRMP, TCL1A, MARCKSL1, SWAP70, CD22, TNFRSF13C, RFTN1
preGCPRDX1, YBX1, NME2, HSP90AB1, MIF, NPM1, EIF4A1, FABP5, LMO2, BASP1
preMature IgG+ PCDERL3, FKBP11, XBP1, MZB1, PRDX4, SEC11C, ITM2C, IGHG3, IGHG4, JCHAIN
preMature IgM+ PCXBP1, LINC02362, FKBP11, DERL3, PRDM1, TXNDC5, CREB3L2, ELL2, SLAMF7, CKAP4
preTCD1E, ARPP21, RAG1, DNTT, LINC01226, AL138899.1, CD1B, CASC15, ELOVL4, PTCRA
Proliferative NBCIGHD, BANK1, RALGPS2, FCER2, LINC02397, MEF2C, NCF1, PARP14, PLAC8, PHACTR1
Reactivated proliferative MBCsSTMN1, PCLAF, MKI67, TYMS, HMGB2, SMC4, SMC2, NUSAP1, DUT, LMNB1
RM CD8 activated TGZMK, CCL5, NKG7, GZMA, CST7, CCL4, IL32, CD3D, CD2, GIMAP7
RM CD8 TGZMK, CCL5, NKG7, CST7, GZMA, CCL4, IL32, CD2, KLRG1, GIMAP7
SCM CD8 TIL7R, LINC00861, CCL5, GZMK, CD8A, CST7, CD8B, KLRK1, GZMA, NKG7
SELENOP Slan-likeLYZ, AIF1, APOE, APOC1, CST3, IL18, TYROBP, ATOX1, PTGDS, LGALS1
Short lived IgM+ PCFKBP11, TXNDC5, DERL3, AC012236.1, CKAP4, LINC02362, CHPF, ELL2, LINC01484, B9D1
Surface epitheliumIL1RN, S100A8, NDRG2, S100A9, SPRR3, TMPRSS11B, KRT13, DUSP5, LCN2, ECM1
T-Eff-MemMAF, CD2, KLRB1, CD3D, GIMAP7, FYB1, GIMAP4, CD3E, CD3G, IL32
T-helperKLRB1, MAF, CD2, RORA, CD3D, SPOCK2, CD3G, CD3E, GIMAP7, IL32
T-Trans-MemKLRB1, IL7R, CD2, GIMAP7, CD3D, RORA, IL32, S100A4, GIMAP4, CD3E
TCRV╬┤+ gd TCCL5, KLRK1, IL32, GZMK, TRGC2, CD7, NKG7, KLRD1, TRG-AS1, GZMM
Tfh T:B borderFYB1, CD3D, IL6ST, IL7R, GIMAP7, CD2, IL32, MAF, SRGN, FYN
Tfh-LZ-GCCD3D, FYB1, CD2, IL32, GIMAP7, MAF, CD3E, CD3G, GIMAP4, PASK
Tfh-MemMAF, CD2, IL32, CD3D, CD3E, KLRB1, CD3G, GIMAP7, TBC1D4, TRAC
TfrIL32, RTKN2, CD3D, CD3E, CD3G, TIGIT, IL7R, FYB1, S100A4, GIMAP7
Transitional PBKIAA0319, AL109761.1, C4BPB, NPIPB6, CKAP4, GGH, GMPPB, AC012447.1, TXNDC5, AP001160.3
VEGFA+TNFAIP2, SPINK5, ITGB8, PDLIM3, RHCG, MIR205HG, DSC2, PTPRF, SFN, VEGFA
ZNF683+ CD8 TNKG7, CCL5, KLRD1, CTSW, GNLY, CST7, KLRK1, ID2, LINC01871, CD8A